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Niacin's Historical Significance and Cardiovascular Risk

Surprising link found between niacin and risk of heart attack and stroke ๐Ÿ”—

Breakdown products of niacin, aka Vitamin B3, may spur vascular inflammation.

The text discusses the historical significance of niacin deficiency, the fortification of foods with niacin to combat pellagra, and a recent study linking high niacin levels to an increased risk of cardiovascular disease. The study found that high blood levels of a breakdown product of niacin were associated with a higher risk of heart attacks, strokes, and death, independent of traditional risk factors. This discovery could potentially lead to new avenues for treatment and prevention of cardiovascular disease.

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