Development of Denoiser-Enhanced PDIC Microscopy for High-Performance Quantitative Phase Imaging

Polarization differential interference contrast microscopy with physics-inspired plug-and-play denoiser for single-shot high-performance quantitative phase imaging - PubMed 🔗

We present single-shot high-performance quantitative phase imaging with a physics-inspired plug-and-play denoiser for polarization differential interference contrast (PDIC) microscopy. The quantitative phase is recovered by the alternating direction method of multipliers (ADMM), balancing total vari …

The text discusses the development of a denoiser-enhanced polarization differential interference contrast (PDIC) microscopy for high-performance quantitative phase imaging. The method uses a custom deep residual U-net (DRUNet) denoiser with an adaptive strategy for phase retrieval, achieving significantly higher quality and accuracy compared to other existing solutions. The study validates the technique on simulated data, phantom experiments, and histological tissue sections.

Single-shot high-performance quantitative phase imaging with PDIC microscopy
Use of a custom deep residual U-net (DRUNet) denoiser with an adaptive strategy
Validation on simulated data, phantom experiments, and histological tissue sections