Physics-Inspired Denoiser for High-Performance Quantitative Phase Imaging

The text discusses the use of a physics-inspired plug-and-play denoiser for polarization differential interference contrast (PDIC) microscopy to achieve high-performance quantitative phase imaging. The denoiser, based on the Tanh activation function, is used in conjunction with the alternating direction method of multipliers (ADMM) to balance total variance regularization. This approach demonstrates significantly higher quality and accuracy in phase imaging compared to other existing solutions. The technique is validated on simulated data, phantom experiments, and histological tissue sections. Additionally, the text cites related works on quantitative phase imaging in biomedicine and other optical diffraction tomography techniques.